Synthesis and evaluation of imidazo[1,5-a]pyrazines as corticotropin releasing hormone receptor ligands

Richard A. Hartz,Paul J. Gilligan,Kausik K. Nanda,Andrew J. Tebben,Larry W. Fitzgerald,Keith Miller

Bioorganic & Medicinal Chemistry Letters（2002）

引用 27|浏览12

暂无评分

摘要

A novel series of imidazo[1,5-a]pyrazines was synthesized and evaluated as corticotropin releasing hormone (CRH) receptor ligands. SAR studies focused primarily on dialkylamino side chain optimization. SAR of the aryl and small alkyl substituents was also explored.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要