Hepatic oxidative alterations in patients with extra-hepatic cholestasis. Effect of surgical drainage.
Journal of Hepatology(2002)
摘要
Background/Aims: The mechanisms of liver injury in conditions of biliary obstruction are poorly understood. Hepatic oxidative injury has been observed in experimental models of cholestasis. Little is known in humans. This study aimed to gain more insights into the hepatic redox status in human cholestasis.
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关键词
Biliary drainage,Hepatic glutathione,Malondialdehyde,Obstructive jaundice,Oxidative stress,Protein sulfhydryl
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