The first regioselective double electrophilic substitution of the C2-symmetric pseudo-meta-disubstituted [2.2]paracyclophanes

Natalia V. Vorontsova,Evgenii V. Vorontsov,Elena V. Sergeeva,Valeria I. Rozenberg

Tetrahedron Letters（2006）

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摘要

Ortho-, para-, and pseudo-gem-regioselective double electrophilic substitution of pseudo-meta-disubstituted [2.2]paracyclophanes gave rise to three possible types of chiral C2-symmetric bis-bifunctional derivatives.

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关键词

Cyclophanes,Electrophilic substitution,Regioselectivity,Bis-bifunctional compounds

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