ON THE USE OF INDEPENDENT COMPONENT ANALYSIS TO REMOVE WATER ARTIFACTS OF 2D NMR PROTEIN SPECTRA

ABSTRACT Multidimensional , H nmr spectra of biomolecules dissolved in light water are contaminated by an intense water artifact. Independent Component,Analysis(ICA) is used to extract a set of signals out of a set of measured,or sensed signals whithout knowing,how,the mixing process is carried out. Hence it is interesting to apply ICA techniques to the re- moval of water artifact in such spectra. Experimental 2D NOESY spectra of proteins are studied.