Influence of Chromatin and Single Strand Binding Proteins on the Activity of an Archaeal MCM

    Journal of Molecular Biology, pp. 1345-1350, 2006.

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    mcmarchaeapatssbssoMore(11+)

    Abstract:

    The mini-chromosome maintenance (MCM) complex is the presumptive replicative helicase in archaea and eukaryotes. In archaea, the MCM is a homo-multimer, in eukaryotes a heterohexamer composed of six related subunits, MCM 2–7. Biochemical studies using naked DNA templates have revealed that archaeal MCMs and a sub-complex of eukaryotic MCM...More

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