Assembly and maturation of pestiviruses

The genus Pestivirus belongs to the family Flaviviridae together with the genera Hepacivirus and Flavivirus. Members of the genus Pestivirus are bovine viral diarrhea viruses (BVDV-1 and BVDV-2), classical swine fever virus (CSFV) and border disease virus (BDV), all of which have a significant economic impact on farming worldwide. Because of their close relationship to Hepatitis C virus (genus Hepacivirus), pestiviruses are studied as a model for this important human pathogen.