Phase IIB/III trial of tenecteplase in acute ischemic stroke: results of a prematurely terminated randomized clinical trial.

E Clarke Haley,John L P Thompson,James C Grotta,Patrick D Lyden,Thomas G Hemmen,Devin L Brown,Christopher Fanale,Richard Libman,Thomas G Kwiatkowski,Rafael H Llinas,Steven R Levine,Karen C Johnston,Richard Buchsbaum,Gilberto Levy,Bruce Levin

STROKE（2010）

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摘要

This prematurely terminated trial has demonstrated the potential efficiency of a novel design in selecting a propitious dose for future study of a new thrombolytic agent for acute stroke. Given the truncation of the trial, no convincing conclusions can be made about the promise of future study of tenecteplase in acute stroke.

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关键词

acute ischemic stroke, tenecteplase, thrombolysis

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