Inhibition of S-ribosylhomocysteinase (LuxS) by substrate analogues modified at the ribosyl C-3 position

Bioorganic & Medicinal Chemistry(2009)

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摘要
S-Ribosylhomocysteine analogues that lack an enolizable hydroxyl group at the carbon-3 position act as competitive inhibitors of the LuxS enzyme.
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关键词
Enzyme inhibition,Fluoro sugars,LuxS enzyme,S-Ribosylhomocysteine
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