ATPase Site Architecture and Helicase Mechanism of an Archaeal MCM

    Molecular Cell, pp. 304-314, 2007.

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    dna

    Abstract:

    The subunits of the presumptive replicative helicase of archaea and eukaryotes, the MCM complex, are members of the AAA+ (ATPase-associated with various cellular activities) family of ATPases. Proteins within this family harness the chemical energy of ATP hydrolysis to perform a broad range of cellular processes. Here, we investigate the ...More

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