AAV9-Mediated Overexpression of Extracellular Superoxide Dismutase Improves Recovery from Surgical Hind-limb Ischemia in BALB/c Mice

Amina Saqib,Konkal-Matt R. Prasad,Arabindra B. Katwal,John M. Sanders,R. John Lye,Brent A. French,Brian H. Annex

Journal of Vascular Surgery（2011）

引用 17|浏览9

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摘要

Conclusion AAV9-mediated overexpression of EcSOD in skeletal muscle significantly improves recovery from hind-limb ischemia in mice, consistent with improved capillary density and perfusion ratios in treated mice.

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hind-limb ischemia,nitric oxide,extracellular superoxide dismutase,aav-9

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