The reaction of epoxyisophorone with ethyl acetoacetate under basic conditions

Tetrahedron(2010)

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摘要
Treatment of epoxyisophorone (1) with ethyl acetoacetate under basic conditions resulted in the stereoselective formation of dihydroxybenzofuran 2 in moderate yield. This result is in contradiction to previous work where similar conditions were reported to afford a bicyclo [4.3.0]nonadienone via a putative Robinson annulation reaction.
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关键词
Epoxyisophorone,Acetoacetate,Furannulation,Benzofuran
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