Novel and known variants in PCSK1 – Functional characterization and clinical associations with obesity in children

A Körner,D Löffler,J Creemers, R Tauscher,J Kratzsch,J Klammt,P Kovacs,W Kiess

Diabetologie Und Stoffwechsel（2010）

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摘要

PCSK1 is a physiologic candidate gene for obesity with support from rare monogenic cases and recent association studies. We aimed to screen the gene for novel variants, to assess their effects on obesity and to evaluate their functional relevance in vitro.

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关键词

pcsk1,obesity

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