A highly active catalyst system for the heteroarylation of acetone

Ping Liu,Thomas J. Jr. Lanza,James P. Jewell,Carrie P. Jones,William K. Hagmann,Linus S. Lin

Tetrahedron Letters（2004）

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摘要

A highly active catalyst system for the heteroarylation of acetone has been identified. The coupling between the in situ generated tributyltin enolate of acetone and a variety of heteroaromatic bromides, chlorides, and triflates in the presence of this catalyst system provided arylacetones in good yields.

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