Identification of genetic loci underlying the phenotypic constructs of autism spectrum disorders.

Xiao-Qing Liu,Stelios Georgiades,Eric Duku,Ann Thompson,Bernie Devlin,Edwin H Cook,Ellen M Wijsman,Andrew D Paterson,Peter Szatmari

Journal of the American Academy of Child and Adolescent Psychiatry（2011）

引用 30|浏览18

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摘要

This study demonstrates that the underlying phenotypic constructs based on the ADI-R algorithm items are replicable in independent datasets, and that the empirically derived factors are suitable and informative in genetic studies of ASD.

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关键词

autism,ADI-R,factor analysis,linkage analysis,quantitative trait

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