Functional Imaging of the Vascular Bed by Dynamic Optical Tomography
PROGRESS IN BIOMEDICAL OPTICS AND IMAGING(2004)
摘要
In this report we present a brief outline of our technological approaches to developing a comprehensive imaging platform suitable for the investigation of the dynamics of the hemoglobin signal in large tissue structures using LAIRS imaging techniques. Our approach includes a combined hardware and software development effort that provides for i) hardware integration, ii) system calibration, iii) data integrity checks, iv) image recovery, v) image enhancement and vi) signal processing. Presented are representative results obtained from human subjects that explore the sensitivity and other capabilities of the measuring system to detect focal hemodynamic responses in the head, breast and limb of volunteers. Results obtained support the contention that time-series LAIRS imaging is a powerful and sensitive technique for exploring the hemodynamics of healthy and diseased tissues.
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关键词
hemodynamic response,measurement system,hemodynamics,near infrared spectroscopy,software development,image restoration,time series,calibration,data integrity,signal processing,functional imaging,computer hardware
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