Prevalence And In Vitro Antimicrobial Susceptibility Patterns Of Acinetobacter Baumannii Strains In A Moroccan University Hospital

Objective. - The aim of this study was to identify the clinical presentations and the current antimicrobial susceptibility of Acinetobacter baumannii.Results. - We identified 754 strains especially from intensive care units (50.53%) between January 2003 and December 2005. Bronchial swabs and blood culture were prevalent. High-level resistance to betalactamines was noted: 91% to cefotaxime, 50.3% to ceflazidime, and 42.6% to imipenem. Aminoside resistance varied from 17.9% for netilmicine to 72.1% for gentamycin. The resistance rate to ciprofloxacine was 65.8%, and to trimethoprime-sulfamethoxazole 75.8%. In intensive care units, the antimicrobial resistance rate of A. baumannii was higher (p < 0.05).Conclusion. - The resistance of A. baumannii to current antibiotics is alarming especially in intensive care units. An effective strategy against nosocomial infection is still necessary. (c) 2007 Elsevier Masson SAS. Tous droits reserves.