Warfarin-induced intracerebral hemorrhage associated with microbleeds.

Background Microbleeds (MBs), proposed as a biomarker for microangiopathy have been suggested as a predictor of spontaneous or thrombolysis-related intracerebral hemorrhage (ICH) in acute ischemic stroke. However, the relationship between MBs and warfarin-induced ICH is not clear. Case Report We describe On patients who developed warfarin-induced ICH at the site of MBs documented in previous MRI. Conclusions The presence of MBs might increase the risk of ICH after warfarin use in ischemic stroke patients. A large cohort study is required to confirm the relationship of MBs with warfarin-induced ICH. J Clin Neurol 2008;4:131-133