Epidemiology of adenovirus type 5 neutralizing antibodies in healthy people and AIDS patients in Guangzhou, southern China

    Vaccine, Volume 29, Issue 22, 2011, Pages 3837-3841.

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    Keywords:
    antibodyaidsvaccineadenovirushivMore(14+)

    Abstract:

    Recombinant adenovirus serotype 5 (Ad5) viruses have been extensively explored as vectors for vaccination or gene therapy. However, one major obstacle to their clinical application is the high prevalence of preexisting anti-Ad5 immunity resulting from natural infection. It has been reported that there are geographic variations in the prev...More

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