Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: improving oral biovailability.
Bioorganic & Medicinal Chemistry Letters（2007）
摘要
SAR studies leading to potent CHK-1 inhibitors with much improved oral biovailability are reported.
更多查看译文
关键词
1,4-Dihydroindeno[1,2-c]pyrazole,Checkpoint kinase 1 inhibitors,CHK-1 inhibitors,Sensitizing DNA-damaging agents
AI 理解论文
溯源树
样例
生成溯源树，研究论文发展脉络
Chat Paper
正在生成论文摘要