Using Enhancing Signals to Improve Specificity of ab initio Splice Site Sensors

CSB, pp. 672-673, 2004.

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exonic splicing enhancerssplicescan programsplice site predictionhuman splice signalsplice site annotationMore(15+)

Abstract:

In this paper, we describe a new approach to improve the precision of splice site annotation in human genes. The problem is known to be extremely challenging since the human splice signals are highly indistinct and frequent cryptic sites confuse signal sensors. There is a strong evidence that Exonic Splicing Enhancers (ESE) and Exonic Spl...More

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