Synthesis of Chlorin-Fused Monospirooxindolopyrrolidines Through a Facile [3 + 2]-Cycloaddition of Azomethine Ylides

P. Saravanan,A. R. Suresh Babu,R. Raghunathan

SYNTHETIC COMMUNICATIONS（2010）

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摘要

One-pot synthesis of novel chlorin-fused monospirooxindolopyrrolidines has been accomplished in good yield via a facile [3+2]-cycloaddition reaction of azomethine ylides, derived from isatin/N-benzylisatin and sarcosine, with various porphyrin derivatives as dipolarophiles.

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关键词

Azomethine ylide,cycloaddition,oxindolopyrrolidines,porphyrin,spiroheterocycles

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