A cross-species comparison of the apolipoprotein B domain that binds to the LDL receptor

Journal of lipid research, Volume 31, Issue 6, 1990, Pages 1109-1120.

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Keywords:
supplementary key words apob-100 ldl receptor apoe receptor binding domain ldl vldl

Abstract:

Apolipoprotein (apo)-B-100 is the ligand that mediates the clearance of low density lipoprotein (LDL) from the circulation by the apoB,E (LDL) receptor pathway. Clearance is mediated by the interaction of a domain enriched in basic amino acid residues on apoB-100 with clusters of acidic residues on the apoB,E (LDL) receptor. A model has b...More

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