Aloe polysaccharides mediated radioprotective effect through the inhibition of apoptosis.

Polysaccharides from aloe are always considered an effective radioprotector on irradiation-induced skin damage. The aim of this study was to determine if aloe polysaccharides (AP) have radioprotective effects on normal human cells in vitro and mouse survival in vivo and to explore the mechanism. Pretreatment with 50 μg/ml AP could improve the surviving fraction at 2 Gy (SF2) of three normal cell l...