Semi-synthesis and anti-proliferative activity evaluation of novel analogues of Honokiol.

Youfu Luo,Yongbin Xu,Lijuan Chen,Jia Hu,Cheng Peng,DaChun Xie,Jianyou Shi,Wencai Huang,Guobin Xu,Ming Peng,Jing Han,Rui Li,Shengyong Yang,Yuquan Wei

Bioorganic & Medicinal Chemistry Letters（2009）

引用 29|浏览11

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摘要

Semi-synthetic honokiol analogues prepared by modifying 5- and/or 3′-position(s) exhibited improved anti-proliferative potencies and displayed more potent anti-drug resistance effects on cisplatin-resistant A2780 human ovarian carcinoma cells.

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关键词

Honokiol,Analogue,Anti-proliferative activity,Anti-drug resistance effect,Semi-synthesis

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