[Expression of CD25+ lymphocytes in nasopharyngeal carcinoma and its association with EBV infection].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University(2006)
摘要
OBJECTIVE:To investigate the expression of CD25(+) lymphocytes in nasopharyngeal carcinoma (NPC) tissue and the influence of Epstein-Barr virus (EBV) infection on CD25 expression.
METHODS:Immunohistochemistry was used to detect CD25 expression in the NPC tissues and in situ hybridization employed to detect EBV infection with chronic nasopharyngitis tissue as the control sample.
RESULTS:Significant difference was noted in the expression of CD25(+) lymphocytes between NPC and chronic inflammatory tissues. The expression was higher in undifferentiated NPC than in keratinizing squamous cell carcinoma and non-keratinizing carcinomas. The NPC tissue was all EBV-positive except for one sample, which was identified as keratinizing carcinoma, but the control samples were all negative for EBV infection, which was correlated with CD25 expression.
CONCLUSION:The expression of CD25(+) lymphocytes is higher in NPC tissues and correlated to EBV infection.
更多查看译文
关键词
in situ hybridization,cd25,nasopharyngeal carcinoma,epstein-barr virus,immunohistochemistry
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要