Combination reperfusion therapy with eptifibatide and reduced-dose tenecteplase for ST-elevation myocardial infarction

Robert P. Giugliano,Matthew T. Roe,Robert A. Harrington,C.Michael Gibson,Uwe Zeymer,Frans Van de Werf,Kenneth W. Baran,Hans-Peter Hobbach,Lynn H. Woodlief,Karen L. Hannan,Sally Greenberg,Joanne Miller,Michael M. Kitt,John Strony,Carolyn H. McCabe,Eugene Braunwald,Robert M. Califf

Journal of the American College of Cardiology（2003）

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摘要

Conclusions Double-bolus eptifibatide (180/2/180) plus half-dose TNK tended to improve angiographic flow and ST-segment resolution compared with TNK monotherapy but was associated with more transfusions and non-cerebral bleeding. Further study is needed before this combination can be recommended for general use.

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关键词

aPTT,CABG,cTFC,ICH,INTEGRITI,MI,PCI,STEMI,TIMI,TMPG,TNK

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