No evidence for linkage of a novel CA repeat polymorphism for apoptosis antigen 1 (APO-1 or fas) with type I diabetes in a Caucasian population.

K Sangthongpitag, K R Moore,N M Lapsys,F Bao,S R Babu,P R Fain,C F Verge

HUMAN HEREDITY（1998）

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摘要

A novel microsatellite marker was found within 48.5 kb of the Fas gene. The observed heterozygosity in 160 healthy unrelated controls was 0.78. There was no evidence of linkage to type I diabetes mellitus in 120 diabetic children using the transmission disequilibrium test.

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关键词

linkage,apoptosis antigen,Fas,CD95,genetics,microsatellite markers

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