A 3 months mild functional test regime does not affect disease parameters in young mdx mice

Neuromuscular disorders : NMD, Volume 20, Issue 4, 2010, Pages 273-280.

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functional testsduchenne muscular dystrophyhistopathologybiomarkersmdx mouseMore(3+)

Abstract:

To assess the effect of potential therapeutic agents in dystrophic mice it is useful to have a functional test regime that does not affect the natural disease progression of mdx mice with dystrophinopathy. We determined the effect of a 12 week test regime consisting of fore limb grip strength, rotarod analysis and two and four limb hangin...More

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