Specific Effect Of T2 Internal Proteins On Viscosity Of T2 Dna

Internal proteins from T2 coliphages have been purified by a new method, involving osmotic shock and chromatography on hydroxylapatite columns. Purified T2 internal proteins interacted specifically with T2 DNA causing folding of the DNA as reflected by significant changes in its viscosity. Internal proteins from T4 phages, similarly affected T4 DNA.