Methylation: a regulator of HIV-1 replication?

Retrovirology（2007）

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摘要

Recent characterizations of methyl transferases as regulators of cellular processes have spurred investigations into how methylation events might influence the HIV-1 life cycle. Emerging evidence suggests that protein-methylation can positively and negatively regulate HIV-1 replication. How DNA- and RNA- methylation might impact HIV-1 is also discussed.

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关键词

Methyl Modification,Protein Arginine Methyltransferases,AdOx Treatment,Protein SPT5,Modify Histone Tail

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