Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells

    Oncogene, Volume 24, Issue 19, 2005, Pages 3177-3186.

    Cited by: 44|Bibtex|Views3|Links
    WOS NATURE
    Keywords:
    ONC oncogenes cancer apoptosis tumor suppressor genesMore(6+)

    Abstract:

    The epidermal growth factor receptor (EGFR) is linked to poor outcome in breast cancer, and resistance to hormonal therapy is often accompanied by activation of growth factor receptors. To investigate the mechanism(s) by which EGFR becomes activated in breast cancer, we screened a cDNA expression library for genes that mediate EGF-indepen...More

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