Clinical Infections and Bacterial Resistance Surveillance of Enterobacter cloacae

OBJECTIVE To investigate the clinical distribution and antimicrobial resistance of infections caused by Enterobacter cloacae in our hospital,for guiding the clinical application of antibiotics reasonably.METHODS Retrospective analysis of the drug resistance situation and specimen distribution was made to the E.cloacae isolated from our hospital in the recent 2 years.RESULTS Totally 148 strains of E.cloacae were isolated between Jan 2005 and Nov 2006,the percentages of these strains isolated from sputum,and urine were 53.4% and 16.2%,respectively; the 148 strains of E.cloacae distributed in many wards,were more sensitive to carbapenem,cefepime,piperacillin/tazobactam,cefoperazone/sulbactam,and moxifloxacin.CONCLUSIONS E.cloacae mainly causes infections of respiratory tract and urinary tract in clinic.E.cloacae is multidrng resistant and severely resistant to third generation cepholosporins,imipenem remains to be the first choice to treat the severe infection which caused by E.cloacae.