Immunoassay Reagents For Psychoactive-Drugs .5. Quantitative-Determination Of Imipramine And Desipramine By Fluorescence Polarization Immunoassay

M Adamczyk,J R Fishpaugh,C A Harrington,P Orsulak,L Akers

THERAPEUTIC DRUG MONITORING（1994）

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摘要

Two methods for the quantitative determination of imipramine (IMI) and desipramine (DMI) by fluorescence polarization immunoassay (FPIA) are described. One immunoassay allows for the accurate quantification of imipramine in the presence of desipramine, while the other allows for the accurate quantification of desipramine in the presence of imipramine.

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关键词

TRICYCLIC ANTIDEPRESSANTS, IMIPRAMINE, DESIPRAMINE, IMMUNOASSAYS, FLUORESCENCE POLARIZATION, HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

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