Oxidant-induced priming of the macrophage involves activation of p38 mitogen-activated protein kinase through an Src-dependent pathway

    Surgery, pp. 242-246, 2003.

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    Keywords:
    cell linemitogen activated protein kinasetranscription factortyrosine kinaseimmune system

    Abstract:

    Background. Resuscitated hemorrhagic shock predisposes patients to the development of organ dysfunction, particularly to lung injury. Ischemia/reperfusion during shock is believed to prime the immune system for an exaggerated inflammatory response to a second delayed stimulus. We previously reported an in vitro model of oxidant-induced pr...More

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