Genetic susceptibility to aminoglycoside ototoxicity: how many are at risk?

Genetics in medicine : official journal of the American College of Medical Genetics, Volume 4, Issue 5, 2002, Pages 336-345.

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To assess the occurrence of two mutations associated with susceptibility to aminoglycoside ototoxicity.Genetic analysis of anonymized, residual diagnostic specimens.One occurrence of the A1555G mutation and seven occurrences of the 961delT + C(n) nucleotide change were found. Two previously unreported sequence changes, T961G and 956-960in...More



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