Multi-Component Reactions in Heterocyclic Chemistry
msra(2011)
摘要
Multi-component and domino reactions are efficient and effective methods in the sustainable and diversity-oriented synthesis
of heterocycles. In particular, transition metal-catalyzed multi-component sequences have recently gained considerable interest.
Based upon the Sonogashira entry to alkynones, alkenones, and intermediate allenes, we have opened new avenues to the one-pot
synthesis of numerous classes of heterocyclic frameworks in an MCR fashion. This methodological approach has now found various
applications in one-pot syntheses of functional chromophores, pharmaceutically active compounds, and marine alkaloids and
derivatives.
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关键词
Tetronic Acid, Pyrimidinium Salt, Trimethyl Orthoformate, Passerini Reaction, Perm State Pharmaceutical Academy
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