Adaptive immune defects and delayed rejection of allogeneic tumor cells in beige mice

The effect of the beige ( bg ) mutation on adaptive allogeneic tumor rejection was examined by monitoring tumor cell survival in vivo using [ 131 I]iododeoxyuridine-prelabeled cells. Accelerated elimination of allogeneic tumor cells normally begins 8 days after ip injection and is due to active immune responses. Two independent mutations ...More