Antithrombin, PC (Protein C), and PS (Protein S): Genome and Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels. Yuekai Ji , Gerard Temprano-Sagrera , Lori A Holle , Allison Bebo , Jennifer Brody , Ngoc-Quynh Le , Kadri Kangro , Michael R Brown , Angel Martinez-Perez , Colleen M Sitlani , Pierre Suchon , Marcus E Kleber , David B Emmert , Ayse Bilge Ozel , Dre'Von A Dobson , Weihong Tang , Dolors Llobet , Russell P Tracy , Jean-François Deleuze , Graciela E Delgado , Martin Gögele , Kerri L Wiggins , Juan Carlos Souto , James S Pankow , Kent D Taylor , David-Alexandre Trégouët , Angela P Moissl , Christian Fuchsberger , Frits R Rosendaal , Alanna C Morrison , Jose Manuel Soria , Mary Cushman , Pierre-Emmanuel Morange , Winfried März , Andrew A Hicks , Karl C Desch , Andrew D Johnson , Paul S de Vries , Alisa S Wolberg , Nicholas L Smith , Maria Sabater-Lleal Arteriosclerosis, thrombosis, and vascular biology（2023）
摘要
The use of larger sample sizes, diverse populations, and a denser imputation reference panel allowed the detection of 7 novel genomic loci associated with plasma antithrombin, PC, and PS levels.
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