Synthesis, SAR, and antibacterial activity of novel oxazolidinone analogues possessing urea functionality.

N Selvakumar,G Govinda Rajulu,K Chandra Shekar Reddy,B Chandra Chary,P Kalyan Kumar,T Madhavi,K Praveena,K Hari Prasada Reddy,Mohammed Takhi,Arundhuti Mallick,P V S Amarnath,Sreenivas Kandepu,Javed Iqbal

Bioorganic & Medicinal Chemistry Letters（2008）

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摘要

The syntheses of a series of novel oxazolidinone analogues possessing an urea functionality are reported. The SAR around the urea functional group resulted in interesting antibacterial compounds.

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关键词

Oxazolidinones,Antibacterial,Linezolid,Urea

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