Coenzyme Q10, Rosuvastatin, and Clinical Outcomes in Heart Failure

John J.V. McMurray,Peter Dunselman,Hans Wedel,John G.F. Cleland,Magnus Lindberg,Åke Hjalmarson,John Kjekshus,Finn Waagstein,Eduard Apetrei,Vivencio Barrios,Michael Böhm,Gabriel Kamenský,Michel Komajda,Vyacheslav Mareev,John Wikstrand

Journal of the American College of Cardiology（2010）

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摘要

Conclusions Coenzyme Q 10 is not an independent prognostic variable in heart failure. Rosuvastatin reduced coenzyme Q 10 , but even in patients with a low baseline coenzyme Q 10 , rosuvastatin treatment was not associated with a significantly worse outcome. (Controlled Rosuvastatin Multinational Study in Heart Failure [CORONA]; NCT00206310 )

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关键词

coenzyme Q10,heart failure,rosuvastatin

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