Modelling individual space–time exposure opportunities: A novel approach to unravelling the genetic or environment disease causation debate

Clive E. Sabel,Paul Boyle,Gillian Raab,Markku Löytönen,Paula Maasilta

Spatial and Spatio-temporal Epidemiology（2009）

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摘要

The aetiology of Amyotrophic Lateral Sclerosis (ALS) is uncertain. While around 10% is assumed to be inherited, the relative influence of genetic versus physical or social environmental factors (or some combination of the two) has yet to be determined.

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关键词

Individual level,Exposure assessment,Residential histories,Space–time clusters,Amyotrophic Lateral Sclerosis (ALS)

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