Host Neutralizing Responses in Hepatitis C Virus Infection

Abstract Hepatitis C virus ,(HCV) is a ,major ,cause ,of hepatitis ,world-wide. The majority of infected individuals,develop ,chronic ,hepatitis ,which ,can ,then ,progress ,to liver ,cirrhosis ,and hepatocellular,carcinoma. ,Spontaneous ,viral clearance ,occurs ,in about ,20-30% of acutely infected individuals and ,results in resolution ,of infection ,without sequaelae. ,Both viral and host factors appear,to play an important role for resolution of acute infection. A large body,of