A medicinal chemistry evaluation of the autoinhibitory domain of calcineurin

Meheryar N. Rivetna,Scott P. Salowe,Richard L. Tolman,A.Brian Jones

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（1995）

引用 6|浏览16

暂无评分

摘要

Truncation of and substitutions in, the 25 amino acid autoinhibitory element of the phosphatase calcineurin indicate that most of the segment is required for inhibition. The peptide does not, therefore, represent a convenient starting point for small molecule drug development.

查看译文

关键词

amino acid,drug development

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要