Insertion of a sequence encoding light chain 3 of microtubule-associated proteins 1A and 1B in a pestivirus genome: connection with virus cytopathogenicity and induction of lethal disease in cattle

    Journal of virology, Volume 72, Issue 5, 1998, Pages 4139-4148.

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    Keywords:
    microtubule associated proteinsprotein biosynthesismicrotubule associated proteintransfectionamino acid sequenceMore(1+)

    Abstract:

    Pestiviruses represent the first RNA viruses for which recombination with cellular protein-coding sequences has been reported. As a result of such recombinations cytopathogenic (cp) pestiviruses can develop from noncytopathogenic (noncp) viruses. In the case of bovine viral diarrhea virus (BVDV), the generation of cp mutants is linked to ...More

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