Clear Cell Epithelial Ovarian Cancer (Mesonephroid): Bad Prognosis Only in Early Stages

Clear cell ovarian carcinoma accounts for 4.5% of all cases of ovarian cancer at this center; 43% of patients presented with stage I disease. Stage for stage patients with advanced disease (II-IV) did no worse than other subtypes of epithelial tumors but patients with stage I disease did significantly worse at both 5 (P < 0.05) and 10 years (P < 0.02). Young age (<60 years), advanced stage, and the presence of vascular invasion are independently poor prognostic factors, while the presence of a predominantly (>75%) papillary or tubulocystic morphological pattern independently predicts a better prognosis.