Schweinfurthins I and J fromMacaranga schweinfurthii

JOURNAL OF NATURAL PRODUCTS(2010)

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摘要
Demand for the experimental antineoplastic agent schweinfurthin A, for developmental testing, prompted it re-collection of leaf material of Macaranga schweinfurthii from the original collection site in Cameroon. During chromatographic purification of the organic solvent extract. analytical UPLC-PDA-TOFMS of stilbene-enriched fractions revealed the presence of six known schweinfurthins and two previously Unknown stilbenes. The structures of these new compounds, schweinfurthins I and J (1 and 2), were elucidated by 1D- and 2D-NMR techniques.
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