Enantioselective synthesis of C3 fluoro-MEP.

Stephanos Ghilagaber,William N Hunter,Rodolfo Marquez

ORGANIC & BIOMOLECULAR CHEMISTRY（2007）

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摘要

The first enantioselective synthesis of C-3 fluoro-MEP is herein reported. The synthetic pathway developed takes advantage of a selective hydrofluorination of a 2,3-epoxy-1-alcohol to introduce the required tertiary fluoride unit.

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enantioselective synthesis,fluoro-mep

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