The bz vitro incorporation of acetate- 1 -C14 into normal and leukemic leukocyte lipids

SUMMARY White blood cells and plasma from normal and leukemic subjects were incubated in the presence of acetate-1-C". The distribution of radioactivity in six lipid fractions of cells and plasma was measured. Leukemic leukocytes incorporated the highest percentage of radio- activity into the phospholipid fractions whereas normal leukocytes incorporated the highest percentage inta the glyceride fractions. There is no conclusive evidence that the differential white cell count had an influence on these observations. The difference may be related to a more active lipid metabolism in leukemic cells.