Endogenous activation by indirect muta-carcinogens and DNA-repair synthesis in mouse-lung fibroblast cultures.
Mutation Research/DNA Repair Reports(1984)
摘要
Cultures of adult mouse-lung fibroblasts have been treated by series of strong and weak muta-carcinogens. Unscheduled DNA synthesis has been measured by quantitative autoradiography using automatic image analysis. Some of the muta-carcinogens (AFB1, DMN, B(a)P, DMBA, MNNG, 4-NQO)_yielded a measurable UDS response, whereas others (2-AA, AFB2, B(e)P, ICR-191) usually known as weak carcinogens, gave no response. The response was not improved by addition of liver S9.
更多查看译文
关键词
dna repair
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要