One-pot approach for the stereoselective synthesis of spirocyclopropyl oxindoles from isatins and arsonium salts

Tetrahedron(2010)

引用 19|浏览7
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摘要
A one-pot approach for highly stereoselective synthesis of spirocyclopropyl oxindoles 3 with good to excellent yields from the reaction of isatins 1 and arsonium salts 2 in the presence of K2CO3 is described. The structure of product 3 was confirmed by 1H NMR, 13C NMR, IR, MS, EA, and X-ray diffraction as well.
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关键词
One-pot synthesis,Stereoselectivity,Spirocyclopropyl oxindoles,Isatins,Arsonium ylides
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